II8 CALSCFUNDMEDIENCEKEIVERSITYOUN2019Hans C. CleversWnt signaling in stem cells and organogenesisTadamitsu KishimotoIL-6: From molecule to medicine2020Aviv RegevSingle Cell Analysis Technology to Understand the Complexity of LifeAtsushi MiyawakiUnveiling Life Science through Innovative Molecular Imaging2021Katalin Karikó (* 2023) Discovery of Specific RNA Modification Leading to mRNAVaccine DevelopmentOsamu NurekiStructural Biology of Key Molecules in Life2022Carl H. JuneDevelopment of CAR-T Cell Therapy as a NovelImmunotherapeutic StrategyYoshihiro Kawaoka Understanding Viral Pathogenicity for the Control ofPandemic Infectious Diseases2023Napoleone FerraraMolecular Basis of Angiogenesis and its ApplicationKazutoshi Mori Molecular Mechanism of the Unfolded Protein Response2024Demis Hassabis (** 2024) Innovation in biomedical research through brain-inspiredartificial intelligenceMitinori Saitou In vitro reconstitution of germ cell development2012Steven A. RosenbergDevelopment of effective immunotherapies for patients with cancerHiroyuki ManoDiscovery of a lung cancer oncogene EML4-ALK and developmentof molecular targeted therapy2013Victor R. Ambros (* 2024) Discovery of microRNAs as a new class of gene regulatorsShigekazu NagataMolecular mechanisms of apoptosis and its physiology2014Karl DeisserothThe realization of optogenetics, and elucidation of brain functionat the neuronal network levelHiroshi Hamada Molecular and cellular mechanisms of left-right asymmetry2015Jeffrey I. GordonHuman gut microbiome and its impact on health and diseaseYoshinori Ohsumi (* 2016) Elucidation of molecular mechanism of autophagy2016Svante Pääbo (* 2022) Molecular elucidation of human originTasuku Honjo (* 2018) Identification of PD-1 and establishment of cancer immunotherapyprinciple by PD-1 blockade2017John E. DickIdentification of cancer stem cellsSeiji Ogawa Development of functional MRI2018Feng ZhangDevelopment of CRISPR/Cas system in mammalian cells andapplication for medical scienceMasashi Yanagisawa Elucidation of sleep control mechanisms and applications indrug discovery
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