II7 CALSCFUNDMEDIENCEKEIVERSITYOUN (* Nobel laureate in Physiology or Medicine, year received) (** Nobel laureate in Chemistry, year received)1996Stanley B. Prusiner (* 1997) Discovery of prions and prion diseasesShigetada NakanishiStudies on the molecular structure and function of glutamate receptors1997Robert A. WeinbergProto-oncogenes, tumor suppressor genes and cancerTadatsugu TaniguchiMolecular biology of cytokine systems1998Moses Judah FolkmanMolecular mechanisms of angiogenesisKatsuhiko MikoshibaMammalian neural induction and brain pattern formation1999Elizabeth Helen Blackburn (* 2009) Telomeres and telemeraseShinya Yoshikawa Three-dimensional structure of bovine heart cytochromec oxidase and relation with enzyme activity2000Arnold J. Levine p53 as a tumor suppressor gene and an important signaling moleculeinvolved in various cellular functionsYusuke Nakamura Elucidation of various genetic diseases through human genome analysis2001Tony HunterIdentification of Sr tyrosine kinase and functional study of cell growthand tumorgenesisMasatoshi Takeichi Discovery of cadherin and studies on the molecular mechanisms ofcell-cell adhesion2002Barry J. Marshall (* 2005) Isolation and cultivation of Helicobacter pylori- pioneering work indiagnosisand treatmentKoichi Tanaka Establishment and development of the living-donor livertransplantation system2003Ronald M. EvansElucidation of the molecular mechanisms of nuclear receptors that linklipid-soluble hormones and vitamins to gene expressionYasushi Miyashita Cerebral mechanisms of cognitive memory2004Roger Y. Tsien (** 2008)Visualization and control of molecules within living cells2005Yoshinori FujiyoshiDevelopment of high-resolution electron cryo-microscopy forthedetermination of membrane protein structures2006Thomas A. Steitz (** 2009) Structural basis of large ribosomal subunit function anddrug development2007Brian J. Druker Development of a molecular-targeted therapy forchronic myelogenous leukemiaHiroaki MitsuyaDevelopment of anti-AIDS drugs2008Fred H. Gage Physiological roles of adult neurogenesis in mammalian brainShimon Sakaguchi (* 2025) Discovery of regulatory T cells and their roles inimmunological diseases2009Jeffrey M. Friedman Discovery of leptin and study of its physiological functionsKenji KangawaDiscovery and clinical application of ghrelin and othernovel bioactive peptides2010Jules A. Hoffmann (* 2011) Discovery of insect-innate immune system and Toll receptorShizuo AkiraElucidation of molecular mechanisms of innate immune responsefor microbes2011Philip A. BeachyIdentification of Hedgehog, a key molecule in development,and its medical applicationsKeiji TanakaDiscovery of proteasome and elucidation of its physiologicalfunctionsPrize Laureates（1996-2024）
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